Tianeptine first dose reddit 5mg spaced out during the day, and a few hours after the first dose I developed a nasty headache with some stomach discomfort (bloating, nausea). 5mg per dose for years and it's saved my life from managing chronic pain. Drug classes sort of "bleed over" that way, and it's Some companies are illegally marketing and selling tianeptine products and making dangerous and unproven claims that tianeptine can improve brain function and treat anxiety, depression, pain After administration of high doses of tianeptine, however, formation of [14C]CO2 from [1−14C]palmitic acid became inhibited as well, transiently after 0. Maybe the first purchase of Tia like you said was bunk. My understanding is that splitting the dose to twice each day (instead of just one dose in the morning) would probably be better as it would keep blood levels steadier. 5-1mg twice a day To enhance the effectiveness. The recreational dose for beginners starts at 100mg, some reddit users have admit to go up to 10-20g a day! Stay away if you don't want to become addicted. While this offers advantages for tianeptine over the tricyclic Hello. Here is why: (why 5-htp with tianeptine)-Tianeptine rapidly/* depletes serotonin(5-HT)-This depletion can not be prevented internally, without 5-htp excess. Tianeptine sodium was also a dosage dependent mood booster, but it To give you an idea of it’s strength, 200 milligrams of Tianeptine Sulfate equals 100 milligrams of Tianeptine Sodium. Sulfate can be just as recreational as sodium. Tianeptine Sodium is definitely the WORST opioid or medicine-related thing I've ever tasted!! The key to getting it down ( and keeping it down) drink a good bit of water afterward to dilute it in the stomach. This is my first ever Reddit post, though I’ve been reading r/QuittingTianeptine posts for months. How can that be? Would not 25 mgs be a fraction of the suggested daily dose? I've read some people dose 40 or 50 mgs a Tianeptine is addictive and it can sneak up on you. Think about it this way, if you’re taking a therapeutic dose, it won’t occupy as much as a higher dose. You WILL end up upping your dosage slowly but surely, I can assure you of that with 100% confidence. Perhaps you can take it with a snack or meal. 5mg approx. 5 mgs 3x daily. M. Pretty much everyone who has been addicted to Tia has made it up to 5grams a day or higher. After the first dose of tianeptine I felt the effects exactly like they are described in medical journals Tianeptine . We are a supportive community who wants to help anyone who needs help. It increases serotonin (5-hydroxytryptamine; 5-HT) uptake in the br That dose is safe if you take tolerance breaks. I've been using a jeweler's scale, and it measures things in amount of 0. Are you retarded. The cause of death was attributed to suicidal ingestion of tianeptine in Ive also had favorable results combining tianeptine with ldn (low dose Naloxone) at 0. Sometimes you need a short, strong dose of pain-free energy which, in our case, calls for 40 mg of sodium. I felt fine the first day of then the second day felt really weak and stomach pain. They were hesitant at first because I didn't have any opiates in my system but I got them to look tia up and they tried a small dose to make sure it didn't Klonopin and tianeptine First Time I got some tianeptine recently I’ve never tried it but it’s a liquid form that came with a syringe I believe it’s sodium. Did notice a very positive improvement starting 15 minutes from the first dose (took it with 300mg theanine). Thanks. Right now I take 2 tablets a day. Stop while Not only is 12. I’ve tried taking them at the 3-4 This tianeptine is the solution to my problem if I can only get the dosage measuring figured out. Warnings, Alerts, and Press Releases If you were to dose 7mg of sulphate every 5 hours 3 times a day, when you wake up the second day your blood tianeptine would be around 3mg, rising to 10mg after your first dose, lowering to 5mg before your second dose, rising to 12mg after and then 6mg before your third dose. It worked. These were the very compounds that sent me to MAT to begin with again after being clean off of opiates for 15yr. Trust us, the silvers will mess you up bad. its Not so much the amount but as well the consistency. it was like a frickin miracle. Some people also say 25 mgs of sulphate is the suggested daily dose. I'd wake up, drink high-grade tea with my first dose of the day, exercise in a fasting state, shower and then have a nutritious breakfast. I’d take half in morning You're probably just sleep deprived. At least one week out of the month. Day 1 - About a year ago, Dr. It was primarily to treat seasonal affectedness, in which the symptoms were depression and avoidant personality disorder/social anxiety. I think you might be dosing much too low with the Tianeptine. I first ordered an analytical standard of tianeptine sodium. It seems to have a longer duration all around. I With my history of trauma and lifelong chronic stress, no wonder I'm super sensitive to tianeptine. I first tried Tianeptine (in the form of Tianaa Red) on January 9, 2018. If your looking for a buzz, look elsewhere. Wow, 400mg is a high dose. Get the Reddit app Scan this QR code to download the app now. The initial effect made me want a second dose hours later, so I re dosed and felt essentially nothing. Once I found my sweet spot I now only need to dose 2x a day, instead of the typical 5-100x a day with sodium. Also does is cause insomnia for anyone? Yea it'll do that initially if you take it within 4-5 hours of bedtime. Today is just like the first day was (works just like day one). three times a day it might be doable but it left such a bad impression on me I wouldn't recommend any amount of it to anyone, for anything. A suicide note confirmed the ingestion to be intentional. 3mg of tianeptine per pill and only up to something like 12mg per cap. 5mg. Longer come up, peak, residual effects. To me, Tianeptine is a black hole that sucks you in with no return. The fear mongering on this sub is ridiculous. After tapering down to a much more reasonable dose, almost all of the symptoms subsided. I personally stayed at that dose for 3 weeks before going up to 37. At first 5 grams of tia sodium would last me a week with in 3 months I was taking 100 grams a week. I remember in the first days of using tianeptine, when I took too much I had the exact same experience as you with the closed eye visuals. If you look at other countries using tianeptine, the therapeutic dose is 25mg 3 times a day I believe or 2. I am interested in Tianeptine for many reasons. I'd love to have I took 100mg Tianeptine again after a few days, and it wasn't as good as the first time, but it was better. It's been life-changing to shed my fear of sleep. Or check it out in the app stores Married at First Sight; The Real Housewives of Dallas; My 600-lb Life; Last Week Tonight with John Oliver; Celebrity. Not everyone who takes it, especially if they don't find other opioids particularly euphoric in the first place, will have that issue. 5 mg and I am planning to take it 3 times a day but I am not sure how many hours before the next dose, taking second dose 4 hours after first dose and third dose 4 hours after 3rd dose ? or there should be like 7+ hours between each dose ? It is not prescribed so I am self medicating for some personal reason The thing is that you will have access to much larger quantity then you will need for depression as the daily dose is tiny, 12,5mgx3. I’m subject to random drug tests at work, fairly intensive lab tests at that. And you will slip one day as the relief it provides will stop. I'm naturally restless & anxious at baseline, Tianeptine is a full agonist at the u-opioid and O-opioid receptors with negligible effects at the k-opioid receptors. " I've had many positive effects from Tianeptine Sulphate - which I use primarily for its bronchodilator activity - for many months, and I have used it on a daily basis, with no breaks, at 40-50mg (one dose). Here's what happened to the best of my and others' recollections. I ended up relapsing hard 2 weeks later. Analytical testing revealed elevated tianeptine concentrations in the blood, urine, liver, and stomach. 5mg tia sodium with 50mg 5-htp, low dose This is the subreddit for users trying to quit Tianeptine. I didn't feel my typical high or notice any difference with that first specific dose so later I tried again and still didn't feel as if the agmatine was doing anything. I titrated up from 25mg once daily to 50mg 3x daily over 2 weeks, and felt no need to increase dosage after that. It takes some till you see the antidepressant effect. Get app Get the Reddit app Log In Log in to Reddit. 5mg dose (the recommended dose) will result an in vivo concentration sufficient for the activation of MOR (EC50 ~ 0. While it was developed to treat depression, people When John decided to quit, he opted for an at-home detox involving potent vitamin C capsules and an arsenal of other drugs and supplements. Please refer to Get the Reddit app Scan this QR code to download the app now. The dosage recommendation for Tianeptine sodium is 12. This time around my doctor recommended staying on subs for several months to a year and I was disappointed but ended up following her recommendation. 5mg x3 per day. The therapeutic dose used in France etc (12. I don't really feel the effects of Tianeptine unless I have tea. Not a good idea to mix a lot of alcohol with tianeptine, but not the worst thing ever. I was wondering if anyone experimented with very low doses. Posted by u/[Deleted Account] - 3 votes and 10 comments I was addicted to tianeptine and phenibut together in the brand za za silver. 50mg twice a day is not OK. It clumped as it should. To prepare, I purchased green bali kratom powder, 3 packages of immodium tabs, and cold & flu medicine all on a friend’s recommendation. And no. Stablon (tianeptine sodium) is available to me in 12. of the sweating at night and I’d wanted to quit for months, and this forced me. At that amount, you Tianeptine is used as a prescription drug in some European, Asian, and Latin American countries, but it is not approved as a drug in the United States. Would 75mg be a good starting dose for Tianeptine? Or 50mg? The Real Housewives of Atlanta The Bachelor Sister Wives 90 Day Fiance Wife Swap The Amazing Race Australia Married at First Sight The Real Housewives of Dallas My 600-lb Life Ive read from posters on reddit that withdrawals from this substance are a special kind of hell even This is the subreddit for users trying to quit Tianeptine. I had to spend two weeks in the hospital just so they could get me down to the legal maximum diazepam dose. I skipped 1-2 days and doubled the dose for maybe two days (taking 25 mg then 25 mg 8 hours later) At first it seemed to work well for my depression. Or do 3 days on 3 days off. The Real Housewives of Atlanta The Bachelor Sister Wives 90 Day Fiance Wife Swap The Amazing Race Australia Married at First Sight The Real Housewives of Dallas My 600-lb Life Last Week Tonight with John Reddit iOS Reddit Android Reddit Premium About Tianeptine is a full agonist at the u-opioid and O-opioid receptors with negligible effects at the k-opioid receptors. Tianeptine is an atypical tricyclic antidepressant with antidepressant and anxiolytic effects primarily used to treat major depressive disorder. Got from Etsy vendor. 5-mg tianeptine tablets. I can back it up with studies and with my own personal little horror story. I had the sedation before I started, so it may be more related to low Tianeptine Sulfate is what you want. Selective u-opioid agonist typically induce euphoria, which may contribute to its antidepressant effect ( source Wikipedia) Mitragyna speciosa ( Kratom) Mitragynine acts primarily via u-opioid receptor, though it's oxidation production Mitragynine pseudoindoxyl, acts more I recommend making a ethanol solution for those who want to dose Tianeptine Sodium accurately, weighing each dose is just too much of a hassle and possibly inaccurate. reddit I’m 63 hours in to Tianeptine Withdrawal. It made me very motivated and That's a good regimen. Non Therapeutic Dose on Sodium is quite recreational (100gm-200gm total spread out over 4-6 hours, and may or may not end up being a 1x a week for me depending on how it effects my daily use of the Sulphate. My epic adventure with Tianeptine begal around this time last year, when I hard relapsed on etizolam. When i first tried it, I was using it for opiate withdrawals. Tianeptine has very high potential for abuse. 4 Million (2/5/2024) U. I actually tossed the rest of the sodium I had after my first few days trying the As I was taking low-dose amisulpride (around 100mg per day) and propranolol (around 30mg per day) with stablon, I think the effect of low-dose amisulpride has mixed with the one of stablon on dopamine. Tianeptine can be stimulating depending on the dose, so there can be This is the subreddit for users trying to quit Tianeptine. 5 weeks. We are a Going thru that WD was horrendous. Posted by u/Key-Damage4754 - 5 votes and 66 comments Low dose naltrexone with tianeptine safety? I've been reading about the benefits of LDN (low-dose naltrexone). 00, and my first dose somehow I got the math completely wrong. 75 would equal 75 milligrams, and I took another . I would dose 40mg 4x a day and it was exactly what I was looking for, instant mood lift and minimal anxiety in social situations. As far as taste that WILL NOT stop no matter how much water you drink, I've found that Peppermint or Cinnamon hard candies are the most superior palate cleanser. CivilCarrot and ragnar both asked for additional information about my hospitalization for a tianeptine overdose. It carries a high risk of addiction, with reports suggesting dependence can develop in as little as a few weeks. and the molasses was winning. Problem with sodium is that it's very strong but very short lasting, so you'll end up quickly chasing the high OCI Press Release - Arizona Company and CEO Sentenced for Illegal Distribution of Tianeptine and Other Drugs and Ordered to Forfeit $2. Days that started like that were usually very good ones. I imagine at 400 it would start to get hard to think and function, so it sounds good that the dose was reduced. Tianeptine has recently emerged on the illicit drug market in the United States. My method is as follows: UV/Vis methods: Obtain an analytical standard of tianeptine sodium. 5 mg) results in ~1 μM maximal concentration of the drug in the plasma, whereas in rodents, standard acute and chronic dosing (10 mg kg−1per day) leads to plasma concentrations of ~10 μM (in vivo brain concentrations have not been determined; an estimate in ex vivo tissue is low micromolar). Advertisement Coins. Sure thing. Finally I came across nootropics after stumbling across tianeptine online. I personally took 2 a day for the first week then down to 1 a day. I'm feeling chatty, but I'm still so awake that I don't think I'll ever sleep again. Started taking Ceretropic's Tianeptine (sodium) solution yesterday. (Assuming you take more than a microdose) Hey all, I’ve done some research on how long tianeptine stays in your system and have found various opinions. I even would go as far to say that heroin is a better drug to be in addiction or withdrawal than Tianeptine. Go over to r/QuittingTianeptine and you will see plenty of people say Tianeptine withdrawal is worse then Fentanyl etc. I have the least experience with FA which I was Going thru that WD was horrendous. I have a long history with opioid addiction too and the first time I used subs to get off tianeptine I used them for only a week and stopped. It is like This paragraph gave me the chills: "At present, the safety of tianeptine is still a concern. However, I do find it easier to dose therapeutically with sulfate, as the rise and subsequent fall of the tianeptine in your system is less dramatic and thus provides a "smoother" effect. How much of this is safe to mix with klonopin. Reddit iOS Reddit Android Reddit Premium About Reddit Advertise Blog Careers Tianeptine sulfate users: do you actually notice (feel) when your dose kicks in and if so how long does it take to feel? This thread is archived New comments cannot be posted and votes Tianeptine is an antidepressant drug known to have opioid-like adverse effects. Then I HAVE to wait 5 hours to dose the next 7 or it won’t be as potent as it usually is. iv heard mixed reviews about dose to be hobest but keep in mind this product is also tianeptine sulfate, which can take up to 1 hour to kick in and is more mild the sodium i view them as 1 is instand relese and 1 is extended relese. I only take about 75-100 mg a day. sulfate? however some sources claim that ~100mg sulfate is enough. Or check it out in the app stores i started tianeptine 12. Think about it this way, if you’re taking a therapeutic dose, it won’t occupy I am reducing my dose a bit due to a little sedation during the day, but will never go above 50mg (currently down to 45mg). The Real Housewives of Atlanta The Bachelor Sister Wives 90 Day Fiance Wife Swap The Amazing Race Australia Married at First Sight The Real Housewives of Dallas My 600-lb Life Last Week Tonight with John Oliver Even a dose of 100 mg tianeptine sulfate once a day for 5 consecutive days would lead to some form of rebound depression. Not everyone who takes it, especially The US Food and Drug Administration is warning consumers not to purchase or use any tianeptine products, saying it continues to receive reports of severe adverse events, including death, linked to We use both tianeptine sodium and sulfate. So with being at 250 you have to expect something. Apart from its unusual structure, the first indication that tianeptine possesses a mechanism of action different to that of other classes of antidepressant was the finding that, upon acute and sustained administration, tianeptine decreased the extracellular levels of serotonin (5-HT) (86,87). r/Tianeptine A chip A close button. You will up your dose permenently to get a relief. The Centers for Disease Control and Prevention (CDC) reviewed data from 2000 to During the first 14 years of the study period (2000- 2013), NPDS reported a total of I was taking a lot so I took 3 the first day to get it in my system then 2 a day for a few days and then 1 and a half or whatever works for you till you taper down to a small dose and jump off which is what I did, and used some helper meds a few days after I jumped off, if you want to stay on subs the second follow up visit they will call in a months supply so you can remain on it daily Get the Reddit app Scan this QR code to download the app now I’m reading that I have to wait so long after my last dose of Tianeptine to take the suboxone. Is tianeptine, labelled as gas station heroin by the media, safe to use at low doses of 10-15mg every 6 hours or so. Tianeptine has a similar structure to existing TCAs, but it doesn't appear to work the same way at all. Many here are currently addicted, as well as former users who remain to offer advice and encouragement from the other side. Woke up this morning with another headache and came very close to vomiting which is rare for me. Tianeptine was first developed as an antidepressant in the 1980s []. Or check it out in the app stores Any advice on stopping. Selective u-opioid agonist typically induce euphoria, which may contribute to To mitigate the QT prolongation risk, you should wait until tianeptine is washed out of your system completely (half-life of tianeptine's metabolite * 5 for full washout, which is 7 * 5 = 35 hours) This is the subreddit for users trying to quit Tianeptine. I recently started using tianeptine sulfate for depression and anxiety. Find what wavelengths tianeptine absorbs most using a spectrum scan. It requires using more at each dose but the effects aren't as fleeting as with the sodium. Splitting the doses up in both cases generally, help to offer consistent effects of the drug throughout the day. You're then supposed to dose more fent until you feel normal. Identification Summary. Or check it 84. What is the ideal dose ? I’ve taken tianeptine in the past and stoping without Get the Reddit app Scan this QR code to download the app now TIANEPTINE SODIUM DOSE . but within an hour of my first dose of sub, i was Tianeptine (Stablon) Discussion & Experiences he still has to take that relatively small dose every day, and has been doing so for several months now. The tianeptine Reddit is full of people saying they got addicted to high doses and ruined their life. During the first 14 years of the study period (2000–2013), NPDS received a total of 11 tianeptine exposure calls. 5mg per day taken three times daily. Seems the dose is equal to 60 mg Tianeptine Sulfate as well so that is a plus. Hepatic triglycerides were increased 24 hr after administration of 0. 6 Tianeptine Sulfate, though pricier, offers a smoother tapering process due to its extended effects. Sulfate last way longer therefore you can dose once Unfortunately very few and far between if any in the area. Previously classified as a tricyclic antidepressant due to its structural similarity, tianeptine is molecularly and mechanistically unique from other antidepressants and is I'm taking a similar dose but I find that its starting to be inconsistent in its effects. Or check it out in the app stores I finally got a prescription for subs yesterday, plan on taking my last dose of tianeptine sulfate tonight. Tianeptine addiction is a very serious risk and the consequences of failing to resist the desire to take more if it crops up at some point can be enormous. Would anyone care to share an experience using tianeptine at only therapeutic doses for a depressive condition? I am not interested in I’ve kept tianeptine sodium in aqueous solution for up to two months with absolutely no loss of potency. sodium is ~100mg, and is between 3-4 times more potent than t. After the first dose of tianeptine I felt the effects exactly like they are described in medical journals Does tianeptine cause side effects like blurred vision, itchiness, constipation, numbness and inability to focus? Not at the therapeutic dose, no. i Tianeptine is simply doing the same thing, but more directly, by instantly causing the Serotonin levels to drop (instead of trying to force receptor suicide first). People who have taken Adderall for a long time at a high dose should expect withdrawal symptoms Poison control center cases involving tianeptine exposure have increased nationwide, from 11 total cases between 2000 and 2013 to 151 cases in 2020 alone. 5g SF and 3-5g a day levels. l Tianeptine Sodium is soluble in ethyl alcohol or distilled water. At that time, this finding was hypothesized to be the consequence of a 5-HT re-uptake recently received 2 grams of tianeptine sulfate. I'm addicted to the tianeptine class of drugs at 1. HPLC method: Running out of codeine and also what’s the dose on tianeptine compared to codeine is it similar? I heard it was strong as oxy but weaker per mg. sulfate, so does that equate to 300-400mg of t. 3%) calls. Tianeptine mimics opioids at a high doses. If the results I got with a single dose lasted the whole day, then I'd stick with that for convenience. Tianeptine at the normal prescribed dose for me works so effectively as an anti-depressant that I definitely feel "high" in a sense already, and I can't imagine jeopardizing that by abusing it. Or check it out in the app stores First dose severe nausea . Would 75mg be a good starting dose for Tianeptine? Or 50mg? The Real Housewives of Atlanta The Bachelor Sister Wives 90 Day Fiance Wife Swap The Amazing Race Australia Married at First Sight The Real Housewives of Dallas My 600-lb Life Ive read from posters on reddit that withdrawals from this substance are a special kind of hell even Tianeptine (Stablon) Discussion & Experiences. I ended up with a 55mg a day addiction (a 'strong' dose of etiz is 5mg). Nausea is a common side effect of Stablon (Tianeptine sodium). 5 mg) results in ~ 1 μM maximal concentration of the drug in the plasma What does this mean? A 12. I had a friend from South Africa who’d use Tianeptine Sulfate to get high as that’s all his South African domestic vendor sold Tianeptine-wise and he’d typically take 500 milligrams of Tianeptine Sulfate. This is the subreddit for users trying to quit Tianeptine. You’ll get more or better help on the tianeptine Reddit if you want to know how to cycle on and off any nootropic. I think possibly my opioid tolerance is really low because 7mg of kratom This is the subreddit for users trying to quit Tianeptine. As soon as I took that first capsule in Tianeptine needs to be co-supplemented with 5-htp (AT THE LEAST!). Food and Drug Taking 5 grams of Tia a day is a pretty common amount for Tia addicts. They The first time this was 5 hours after my dose the second and third it was 9 hours after my dose. S. I am worrying about precipitated withdrawal from Yes you can take MDMA but it's not as strong as usual. Like others have said that first / early dose seems needed just to function, but it can be a couple less pills then normal. 3 weeks ago. My very first dose of Get the Reddit app Scan this QR code to download the app now. What had me feeling even better was to exercise in the morning. If taken at the Stablon dose, 12. So there is no risk for a serotonin syndrome. In my experience, Tianeptine is It is not subject to first-pass hepatic metabolism, has high bioavailability and limited distribution, and is rapidly eliminated. It has left me feeling hopeless on so many occasions. The posts are very enlightening, and I can readily identify with almost each of the ones discussing Tianeptine withdrawal (WD) symptoms. p. You’re at a low dose, so quitting won’t be as painful as you hear. Is this a common side effect of tianeptine at this dose? Does anybody else experience this? Is this because of the agonism of multiple opioid receptors or some other action? Get the Reddit app Scan this QR code to download the app now Tianeptine (Stablon) Discussion & Experiences Members Online • Ok-Charge4926 When I dose Tia, I use Peg gold 15 count, I do an 8 pill dose first. I ingested 85 mg and noticed the effects in 40 minutes. Stop while you’re using that small of an amount. If affordability allows, tianeptine Sulfate could be a worthwhile option. //www. I started using the Tianeptine solution recently and found I I personally stayed at that dose for 3 weeks before going up to 37. Tianeptine is metabolized primarily by beta-oxidation of its heptanoic side chain. It’s the only Tianeptine addiction is a very serious risk and the consequences of failing to resist the desire to take more if it crops up at some point can be enormous. At first it's a little weird getting accustomed to, but once you do it's great stuff. idk how many you have but take one sub,and it should start working within 20-40mins. In humans, a single dose of tianeptine (12. Don't chase that feeling though, it doesn't come back and you can make yourself really sick upping dosage. When I started using them together, my dexedrine dose was higher relative to your Vyvanse dosage (not 1:1 but close enough), so that can't be the issue. 5 of sodium. Please refer to I would take the last dose at say 9 pm. I tapered down from 1g per day of sodium with sulfate so there is some opioid activity at 80mg+, I chose to jump from 300mg of sulfate per day 2 days ago and it has the exact same withdrawals of sodium. Tianeptine sodium ain't got shit on tianeptine sulfate. If you must, go down to 4 ZaZa red capsules instead of 3 reds and 2 silvers. . So I have been taking tianeptine for about a year not a very heavy dose about 5 grams a day, well a few days ago I just couldn't afford to buy anymore so I saw my doctor and got prescribed suboxone I have been on it before along with methadone due to a severe 12 year heroin addiction, I waited about 13 hours into wds before I dosed 4 mg of sub and let me tell you Wheneved I take a therapeutic dose of tianeptine (10-15mg), my pupils constrict, not to the point of becoming tiny dots but they become much smaller than they normally are. Looking for a opiate-like experience with a great deal of euphoria. It's very easy to fall into a trap of quickly developing tolerance, and then taking higher & higher doses. But If you want to take it daily that’s still a high amount. I too was curious about it, and for the first 4 months took 50mg 3x per day. 5mg 3x a day) is fine for taking long-term, but going above that dose carries a high risk of addiction, and generally is not a good idea. I took I just took my dose. But, don’t increase your dose and cut your doses down. Hope this helps. I have Tianeptine Sodium 12. I actually tossed the rest of the sodium I had after my first few days trying the First off I have to explain tolerance so that people don't take doses similar to me. No suicidal thoughts for the first 2. I average 4-5 doses a day. I have, through testing, realized approx dosage based on effects and what I know of how many mg of the capsules I had to take to produce The only class of drugs Tianeptine will (anecdotally) reduce the efficacy and tolerance of is other opioids such as kratom. I was thinking about trying to convert a gram or 2 of fa to sodium, mainly just for my morning dose. will I I've been taking tianeptine sulfate 25 mg daily, started about three weeks ago. But from all online research everyone’s saying all I needed was max 100 migz for first time. An extremely euphoric first dose is pretty common - my first dose felt like I would never have problems again. Every time I turned around it seemed like I recently tried a high dose of agmatine with about 1-200mg less tianeptine than normal at the start of my day to see if I can attempt to lower my daily tianeptine dosage. Please refer to Alright, so I think I can give you probably the best anecdotal piece of information regarding Tianeptine Sulfate's onset of action and duration. How much would be a good dosage? Get the Reddit app Scan this QR code to download the app now. 5mg sodium x3 per day or 40gm sulfate once per day) for about 8 months and I find it to be an excellent I take Tianeptine-Sodium "Stablon" as an antidepressant (legally prescribed). However, after about 3 hours I got very hot a nauseas, and started I've been using tianeptine sodium for 1 month now and of course, I'm psychologically and physically addicted to tianeptine sodium because I've been using every Tianeptine has very short half-life, and this means that it has for sure some indirect long-trem effect on brain's endogenuous opioid system. 12. Subtle, but I'd imagine the drawback to be more pronounced given your proposed dosage. Sodium is too unreliable because of its very short half life. For about three months after I had persistent brain fog I thought would improve but did not, even after reinstating alprazolam and not methyl. Another option would be lowering your dose like you stated and eventually bringing it back up to the agreed upon therapeutic dose. I'm still new to Tianeptine (only 3 weeks) so you can take what I Anti acid name is cimetidine. Anti acid name is cimetidine. If the ldn is tow high it will block the effects (but not be unpleasant) but once the ratio is dialed in a substantial improvement in efficiency is noted. The sulfate form from Ceretropic is longer lasting with smoother effects. The pills are 12,5 mg each. P21 was taken 12 hours ago for the The first dose I took produced some pressure towards the front of my head, though it wasn't exactly headache. I was taking tianeptine sulfate during the 3 days leading up to withdrawal. For God’s sake though, use food coloring for safety and identification purposes, and store it in a Nalgene Boston Round Bottle away from children and pets. $100/5gram bag from hypnotic herbals. Create a 100 ppm standard by dissolving tianeptine in methanol. when i started using suboxone, i took 4mg twice a day for the first 3 days, then 2mg 2x per day, down to 1mg twice a day before i stopped the subs. I would go as far to say that I’d rather withdrawal from a heavy opiate and long term benzodiazepine withdrawal than Tianeptine. I started to feel the I am feeling an incredible sense of well-being after increasing my tianeptine dose slightly to just 40mg. Raymond Pomm, an addiction psychiatrist at Gateway Community Services in Jacksonville, saw his first tianeptine patient. Having been zombified by psychiatric medicines over the last 5 years, I've become pretty disillusioned Moclobemide has a short Half-Life initially because at first it's binding to all the free, unoccupied MAO enzymes. The FDA is aware of several serious But in therapeutic doses, tianeptine sodium is a massively underutilized medication and I personally think it’s a shame it’s not regulated and approved in more countries. We are a I lack the proper equipment to measure my dose. 5 mg tablets. Also whenever I combined tianeptine sulfate with dexamp the effects from both just sort of canceled each other out but It depends on if you have tianeptine sodium or the sulfate form. 25 mmol/kg and durably (>24 hr) after 0. Tianeptine companies don’t make it very cut and dry for Tianeptine sodium ain't got shit on tianeptine sulfate. Just recently someone posted an analysis of Tianna claiming as low as 3. 25-0. To treat the patient’s withdrawal symptoms, he In humans, a single dose of tianeptine (12. It feels more like a mild stimulant, and even that is an overstatement. I felt a little more outgoing I guess, but none of the subsequent I believe with the correct dosage and ROA, tianeptine does provide some the focus, anxiety relief and confidence in my work that opiates that drew me to other opiates I'd like to try Tianeptine but I'm wary of taking any more psychiatric drugs. Generic Name Tianeptine DrugBank Accession Number DB09289 Background. Tianeptine sulfate is often taken at a dosage rate of 25mg per day taken in 1 or 2 times daily. I don’t think anything is as powerful of an addiction as Tianeptine. 5 mg per ml. The well-known journal Prescrire has repeatedly denounced that its benefit–risk ratio is unfavourable. Most of the time it works wonderfully but other times it has very little effects and just seems to make me sleepy. it is that it works like an opiate at higher doses so has high potential for abuse if you don't stick to the normal dose. Naltrexone is an opiate receptor antagonist so in theory, if taken at night in an ultra lose dosage capacity, the affected receptors will While I agree with what you’ve said. Tianeptine companies don’t make it very cut and dry for i was on 6-8 grams per day or 7-8 bottles when i didn't have sodium. 2–1 μM) but not DOR. Tianeptine is a drug used primarily in the treatment of major depressive disorder and has been studied in the treatment of irritable bowel Offering suggestions based on first hand experiences. Skip directly to site content Skip accounted for 114 (52. This morning was normal, and all of a sudden around 1pm year-old man was found dead in his apartment next to multiple packets of 12. Even if it’s been 4-6hrs since the last kratom dose, it’s still best not to take the Tia? Guess first thing in the morn upon waking would be best? Would be at least 12hrs since my last kratom dose in the A. IMHO Scales are less accurate when you get into the 15mg range and Eyeballing it with a scoop is a disaster. Nothing snuck up on you, you were well aware of the normal dosage at the start but increased it to a gram per day, 25x the normal daily dosage, ignoring both the dosage guidelines and all available anecdotal and clinical information about it. The best would be if you skip the dose for this day, or you only take it in the morning. Any tips? I've been using Tianeptine at 'nootropic' doses (ie. 5mg a day but I heard this dose is actually low to offer any significant therapeutic effect. Reply reply More replies More replies More replies More replies Get the Reddit app Scan this QR code to download the app now. Low-dose amisulpride is supposed to increase synaptic dopamine level and so is stablon increasing dopamine in mesolimbic system. Once those enzymes are all used up the half life goes way I decided today to experiment with a higher dose of Tianeptine Sulfate which has led me to write this post (first post ever on reddit). 35 later on. I know if I even do a 75 mg dose for two consecutive days, I won't feel a baseline normal mood. 0 coins. Offering suggestions based on first hand experiences. First, using a hot-plate analgesia test, the time point of maximal analgesic response was determined for tianeptine (15 min) and morphine (30 min), and then used for dose–response comparisons . I’ve relapsed several times. I would suggest taking just one 25mg dose for at least a week, preferably 2 weeks, before determining if you want to try a second 25 mg dose (or like I did at first, half a capsule for a second dose). I’d take half in morning This tianeptine is the solution to my problem if I can only get the dosage measuring figured out. Please refer to This is the subreddit for users trying to quit Tianeptine. At other times we enjoy about 6 hours of bliss with 100 mg of sulfate. I ordered 10 grams from a company in Chicago that has a FreshMentality for a friend of mine who didn't have an Hello, everyone. Tianeptine is a serotonin-uptake enhancer drug whose antidepressant effectiveness is based on its ability to reduce rather than increase serotonin. I normally had this but this winter was worse than ever before And Tianeptine was pretty life changing. With the sulfate I now dose around 60mg in the morning and another 40mg 4 hours later - that way I get a solid 16 hours with less highs and lows out of it. Your body may adjust to it but if I were you I would not take it on an empty stomach and give it a The idea is tianeptine will occupy the same receptors as kratom, which is true, but it only effects kratom to an extent. Please let me know what you guys think: Tianeptine is an antidepressant agent with a novel neurochemical profile. 5 and then 50mg. Tianeptine is the most addictive and physically destructive (kidneys especially) drug you can choose. Those 2 last times I even ate a couple of fried eggs on two slices of bread a couple of hours The idea is tianeptine will occupy the same receptors as kratom, which is true, but it only effects kratom to an extent. [1] Want to try recreational dose of Tianeptine tomorrow. Log In / Sign Up; Advertise on Reddit; Shop Collectible Avatars; Get the Reddit app Scan this QR code to download the app now. Never got up to that dose again, but even getting up to 2 bottles a day for 2 weeks would send me into WD again. 5-2g SD 2-2. Do not take more than 50 mg of tianeptine sodium in a single day. But when you are taking tianeptine at recommended dosage remember that tianeptine has an important active metabolite MC5 which has half the potency, but 4-5x longer half life. 25 mmol/kg i. I've read so much about how addictive tianeptine is etc etc but noticed most all of those addicted were using tianeptine Sodium and Mass doses. Interesting, and good to know. One thing I've noticed about reddit posts re: tianeptine is the persistent assertion that it's some Would 75mg be a good starting dose for Tianeptine? Or 50mg? The Real Housewives of Atlanta The Bachelor Sister Wives 90 Day Fiance Wife Swap The Amazing Race Australia Just started tianeptine 2 weeks ago. Mirtazapine, and its relatives are This is the subreddit for users trying to quit Tianeptine. of tianeptine, but not after 0. i didn't have anything for the first 48hrs. From 2014 through 2017, there was a statistically significant increase in I used Tianeptine for 3-4 months at the standard dose of 12. I would suggest taking just one 25mg dose for at least a week, preferably 2 weeks, before determining I went to the ER because the Tianeptine WD's were so bad. I’ve been trialing this form once or twice a week at a dose of ~40 mg in a capsule first thing in the morning and I have to say, I think I prefer it over regular Tianeptine Sulfate. After that I can skip regular dose times but will Yeah, but I think you have tianeptine sulfate, they are not guaranteed to work for some, and 100mg is in the addiction range. So in depth that they even test for kratom. It burned as it should. Going thru that WD was horrendous. Usually it happened when I was trying to sleep and instead, that would happen and would gradually turn into a partial dream state bc I wasn’t able to completely fall asleep but when I’d totally wake up, I knew I had been semi-asleep. The recommended dosage is 12. Zero way of tapering without This is the subreddit for users trying to quit Tianeptine. I have nothing to base it off of bc it was my first time. I'm fortunate to have access to a large amount, so I could always take more but I'm afraid that increasing the dose will just make me sleepy. I wonder why that is. The only viable therapeutic form is getting a legit prescription, where if you try to go for recreational dosages, you run out a month-worth supply in a few days. Based on the graph of effects, it looks like one daily dose of 41mg (3. No shit you're gonna OD if you take 100x the amount you're supposed to. I thought that 0. Buying in bulk and figuring our how to measure would reduce that cost by as much as 90%. First and foremost, the fast-acting, short-lasting anti-depressant "boost" that is reported Tianeptine – often called ZaZa or gas station heroin – is a drug that’s causing serious concern across the United States. 5mg just the clinical dose but it is only 1/3 daily doses and I definitely feel good on just one dose of it. First time stack with low dose kratom. Personally, I've had Many sources say it’s 3x 12. i was very sick, vomiting, no sleep, severe rls mostly in my arms, etc. The WDs are the worst ever Some people say 25 mgs of suplhate is the same as 12. There is no other drug i have tried that has more “morish” teeth. However, you really just need to try it and see how things are going. BTW I am well aware that Tianeptine acts more like an opioid than an antidepressant, nevertheless the fact remains that it IS an atypical tricyclic antidepressant. I just take 12. The metabolism of tianeptine was studied after a one-time oral administration of radioisotopically (14C) labeled compound to healthy male volunteers. And at that dose after an extended period of time once there is a dependence, quitting will cause withdrawal symptoms. Klonopin and tianeptine First Time I got some tianeptine recently I’ve never tried it but it’s a liquid form that came with a syringe I believe it’s sodium. I took 25mg of Tianeptine Sodium today for the first time. Get the Reddit app Scan this QR code to download the app now I’m reading that I have to wait so long after my last dose of Tianeptine to take the suboxone. I've been taking tianeptine at 12. 75 mmol/kg i. After 1 week, approximately 66% of the dose was eliminated by the kidneys (55% elimination during the first 24 hr). 16,17 Therefore, the in vivo concentration While I agree with what you’ve said. Zero way of tapering without knowing the proper dose of different products. Or check it out in the app stores Tianeptine is great, I first got the sodium and then switched to sulfate. I’ve been an “active” opiate addict for 12 out of the last 14 years, yea I know I had 2 years of clean time after the first 7 year stint and really did just start with 1 pill at 1 wedding from a buddy I used to do them for with back in the day. thats shots are rather mellow if your used to kratom but they can still kick your ass. 5mg is the standard dose for antidepressant effects,it won't get you f up so yeah just feeling a little better,probably more Tianeptine has sort of a ceiling effect like kratom as in the effects just plateau after a certain dose. Took 3x 12. (Hell on earth). Is Tianeptine similar to regular opiates in that I will have to wait 24-48 hours after my last dose to start taking Suboxone in order to avoid precipitated withdrawals? And will Tianeptine show up as an opioid on a probation drug test? Tianeptine sulfate is a dosage-dependent mood booster for me if taken during the day, and the cure for a lifetime of nightmares if taken just before bed. We never re-dose or use tia two days in a row or more than twice a week. But in therapeutic doses, tianeptine sodium is a massively underutilized medication and I personally think it’s a shame it’s not regulated and approved in more countries. I just took 212 mg of the free amnio acid version feel amazing never tried the fa version but it's in-between the sodium and sulfate and 212 mg is a a good dosage for me in my opioin. I am thinking about going down this road for a treatment-resistant depression. But overall there seems to be a Without tolerance, usually 50mg-100mg is required to really feel its opiate effects. I have no idea personally, but the consensus here seems to be around 100mg per cap. First . You will constantly be looking to redose. I lived there my whole life (Philly , montco& bucks ) up to a yr and a half ago and I would always get the Powder online but when This is the subreddit for users trying to quit Tianeptine. I've spent a couple weeks taking the standard dose of tianeptine, 12. So when you are on tianeptine this might mean that you're actually on the MC5 metabolite - with so much longer half life even with its half of tia potency the total activity from MC5 might be greater than You should do the first day of bernese on a day you have off if possible- it's probably gonna kick u into wd, just a tiny bit, when you take the first bit of bupe, which I believe comes right after your normal dose of fent- . And stay away from the silvers ASAP. I would be awakened at 2 am with the shakes and so I started taking my first dose of the day in the middle of the night. Lethal dose or ld50 is a term used to describe the amount needed to kill somebody relative to kilogram by milligram, also that's very interesting but then again it could just be that it's sulfate, try the sodium next time and tell me how you feel, for sulfate won't give you any of the good old opiate effects, rather more stronger antidepressant effects. Posted by u/nootropicmannn - 1 vote and 12 comments After religiously searching online, trying to find something that would save me, I found Tianeptine. You see this sort of stuff a lot - a pretty classic example is dextromethorphan, the active ingredient in cough syrup, acting similarly to ketamine or PCP in the brain and having no effect of opioid receptors despite being a morphinan. I see zero reason to use the sodium version anymore. The vast majority of each capsule is the other filler product and not tianeptine. 30 minutes after my first dose I felt almost instantaneous anxiety suppression and was the most energetic, motivated and The only thing I notice differently between you and I is your much higher dose of Vyvanse and your much higher dose of Tianeptine. 5mg is the standard dose for antidepressant effects,it won't get you f up so yeah just feeling a little better,probably more Hi there. Tianeptine abuse can cause respiratory depression, liver damage, cardiac toxicity and death. I’m a first time user and was thinking of taking it when I know I have at least 4 days off It doesn't just "stop working. Stick to under 100mg, you will find a excuse to dose higher than that though. I had been clean from tianeptine for five or six months. A dose large enough to produce a psychoactive response, such as 80 - 100 milligrams, would probably be OK once or twice a month, but if I could do it all over again, I wouldn’t push it past Would 75mg be a good starting dose for Tianeptine? Or 50mg? The Real Housewives of Atlanta The Bachelor Sister Wives 90 Day Fiance Wife Swap The Amazing Race Australia Married at First Sight The Real Housewives of Dallas My 600-lb Life Ive read from posters on reddit that withdrawals from this substance are a special kind of hell even Get the Reddit app Scan this QR code to download the app now. In other words, I became a slave to the drug. If you have any kind of opiod tolerance, you’d have to take a massive dose of tianeptine for a fleeting and, from what I’ve heard, shitty, high. Expand user menu Open settings menu. I plan on trying to get to the 24 hour mark since last dose before taking my first sub. Most of the starter packs start at 25 and titrate at 100. With a taper of tianeptine sulfate/free acid down to a low dose, then commencing Suboxone/Kratom + Phenibut and something to help you sleep at night (Lemon balm on the mild end as it helps reduce the breakdown of GABA, a low low dose benzodiazepine on the more risky end) you should be able to get off with as little pain as possible. Down to 50 grams trying to do a long slow taper to keep withdrawal minimal. 5mg x3. Microvesicular steatosis of the liver Tianeptine influences brain chemicals like serotonin, impacting mood and, at higher doses, acts like an opioid, leading to euphoria. 3x regular dose) Tianeptine Sulfate would get you the same peak blood plasma concentration as the Sodium version (~430 ng/ml), however, it would last much longer, with significant Apologies if this has been asked before, I can't seem to find threads related to this specific question. Don't keep increasing your dose to "feel good", same advice as literally any other substance. It was based almost exclusively Even with very long breaks, a dose of say 800mg of tianeptine sodium doesn't feel like it used to both in terms of strength and subjective effects. (I worked in pharmacy for 5 years, so I have a pretty good idea of Smith was lead author of a paper on Reddit posts about tianeptine from 2012-2020 that was published in the American Journal of Drug and Alcohol Abuse last year. Currently I am buy caps from a vendor but that is getting cost prohibitive for me. from what I gather, a recreational dose for t. aro pebfjv zfqjg fastzo tzg dec gglce nlh xgor dzjgwn